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Old 09-03-2020, 10:59 AM   #21 (permalink)
Apia resurrected
Senior Member
Join Date: Mar 2020
Location: Niedernhausen, Germany
Posts: 2,641
With the exception of genotoxic oncology drugs, first-in-human, Phase 1 clinical studies of investigational drugs have traditionally been conducted in healthy volunteers (HVs). The primary goal of these studies is to investigate the pharmacokinetics and pharmacodynamics of a novel drug candidate, determine appropriate dosing, and document safety and tolerability.


The alternative would be giving an already sick person a substance never used
In humans before.
The possible risks would affect someone who is already sick much more.

Last edited by Apia resurrected; 09-03-2020 at 11:03 AM.
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